Villa Arceno (or di Arceno) is located in San Gusmè in the municipality of Castelnuovo Berardenga in the province of Siena.
Arceno is documented as a village since the 11th century, when it was donated by Count Guinigi della Berardenga to the abbots of Fontebuona, a possession later confirmed by Alexander III and, in 1185, by Urban III. In 1202 the village entered the financial and political circle of Siena, lending loyalty to the city authorities. In 1223 all the properties in Arceno were granted by the monks in emphyteusis to the lords of Montalto.
In 1671 a villa was built there at the behest of the knight Flaminio Del Taia.  Around the early nineteenth century the property passed to Emilio Innocenzo Piccolomini Clementini, who renovated the building and created the immense park that surrounds it, commissioning Agostino Fantastici, who in those same years also built his palace in Siena. In 1847 Arceno passed to Giorgio d'Innocenzo Piccolomini Crescentini and in 1856 it was sold by him to Giovanni and Domenico Camaioni, and then, on May 18, 1868, to Aristide Castelli di Domenico and, in 1876, to Gino Gamba Nicolai. Frequent changes of ownership reduced the villa to a state of semi-neglect, from which it came out in 1992, when it was completely restored and transformed into a luxury resort and winery;  in 1994 it was bought by Jess Jackson and Barbara Banke.